논문
실적
Publications
Gaire BP*, Lee CH*, Kim W*, Sapkota A, Lee DY and Choi JW. (2020). Lysophosphatidic acid receptor 5-mediated NLRP3
inflammasome activation in macrophages drives imiquimod-induced psoriasis. Cells 9, 1753. (*co-first authors)
Kim DH*, Kim WD*, Lee SJ† and Moon DH†. (2020). TGF1-mediated repression of SLC7A11 drives vulnerability to GPX4
inhibition in hepatocellular carcinoma cells. Cell Death & Disease 11, 406. (*co-first authors) (†co-corresponding)
Simic P, Kim W, Zhou W, Pierce KA, Chang W, Sykes DB, Aziz NB, Elmariah S, Ngo D, Pajevic PD, Govea N, Kestenbaum
BR, de Boer IH, Cheng Z, Christov M, Chun J, Leaf DE, Waikar SS, Tager AM, Gerszten RE, Thadhani RI, Clish CB,
Jüppner H, Wein MN, Rhee EP. (2020). Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney.
Journal of Clinical Investigation 130, 1513-152.
Kim W, Deik A, Gonzalez C, Gonzalez ME, Fu F, Ferrari M, Churchhouse CL, Florez JC, Jacobs SBR, Clish CB† and Rhee
EP†. (2019). Polyunsaturated fatty acid desaturation is a mechanism for glycolytic NAD+ recycling. Cell Metabolism
29, 856-870.e7. (†co-corresponding)
[Previewed by Lutkewitte et al., Fatty acid desaturation gets a NAD+ reputation. Cell Metabolism 29, 790-792]
Jang HY*, Kim DH*, Lee HJ, Kim WD, Kim SY, Hwang JJ, Lee SJ† and Moon DH†. (2019). Schedule-dependent synergistic
effects of 5-fluorouracil and selumetinib in KRAS or BRAF mutant colon cancer models. Biochemical Pharmacology 160,
110-120. (*equal contribution) (†co-corresponding)
Joo MS*, Kim WD*, Lee KY, Kim JH, Koo JH and Kim SG. (2016). AMPK facilitates nuclear accumulation of Nrf2 by
phosphorylating at serine 550. Molecular and Cellular Biology 36, 1931-42. (*co-first authors)
[Spotlighted as an Article of Significant Interest Selected from This Issue by the Editors]
Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP and
Parikh SM. (2016). PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection. Nature 531,
528-32.
Lee CG, Kim JG, Kim HJ, Kwon HK, Cho IJ, Choi DW, Lee WH, Kim WD, Hwang SJ, Choi S and Kim SG. (2014). Discovery of
an integrative network of microRNAs and transcriptomics changes for acute kidney injury. Kidney International 86,
943-53.
Kim WD, Kim YW, Cho IJ, Lee CH and Kim SG. (2012). E-Cadherin inhibits nuclear accumulation of Nrf2 by making an
inactive pool of Nrf2: An implication in chemoresistance of cancer cells. Journal of Cell Science 125, 1284-95.
Kay HY*, Kim WD*, Hwang SJ, Choi HS, Gilroy RK, Wan YJ and Kim SG. (2011). Nrf2 inhibits LXRα-dependent hepatic
lipogenesis by competing with FXR for acetylase binding. Antioxidants & Redox Signaling 15, 2135-46. (*co-first
authors)
Lee SJ, Yang JW, Cho IJ, Kim WD, Cho MK, Lee CH and Kim SG. (2009). The gep oncogenes, Galpha12 and Galpha13,
upregulate the transforming growth factor-beta1 gene. Oncogene 28, 1230-40.
Cho MK*, Kim WD*, Ki SH, Hwang JI, Choi S, Lee CH and Kim SG. (2007). Role of Galpha12 and Galpha13 as novel
switches for the activity of Nrf2, a key antioxidative transcription factor. Molecular and Cellular Biology 27,
6195-208. (*co-first authors)
Kim MS, Lee SM, Kim WD, Ki SH, Moon A, Lee CH and Kim SG. (2007). Galpha12/13 basally regulates p53 through Mdm4
expression. Molecular Cancer Research 5, 473-84.